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REVIEW ARTICLE
Year : 2018  |  Volume : 2  |  Issue : 1  |  Page : 6-11

Cytokeratin: Areview on current concepts


1 Department of Oral and Maxillofacial Pathology, PSM College of Dental Science and Research, Trichur, Kerala, India
2 Research Assistant, Prince Philip Dental Hospital, University of Hong Kong, Hong Kong

Correspondence Address:
Anoop Kumar
Department of Oral and Maxillofacial Pathology, PSM College of Dental Science and Research, Trichur, Kerala, India, Research Assistant, Prince Philip Dental Hospital, University of Hong Kong
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijofb.ijofb_3_18

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Cytokeratins are proteins which form the intermediate filaments and form the major cytoskeleton of the epithelial cells. It has an enormous role in providing mechanical support to the cell. There are various kinds of cytokeratins each showing varied expression in the epithelium. The cytokeratins can be broadly classified into typeI or acidic and typeII or basic proteins. The expression of these plays a role in differentiating different types of epithelial cells, thus enabling us to classify tumors. They help in diagnosing different types of tumors and thus have a vital role in diagnostic pathology.


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